I-Stem Cell Therapy ye-Type 1 Diabetes
Ngokufunda inqaku lethu malunga noNyango lweStem Cell kuHlobo loku-1 lwesifo seswekile, olulolona nyango lukhethwayo mva nje, unokuba nolwazi oluneenkcukacha malunga neekliniki onokulufumana unyango kunye namazinga azo okuphumelela.
Yintoni i-Type 1 Diabetes?
Isifo seswekile luhlobo lwesifo esikhula ngenxa yokuba udakada lungavelisi i-insulin eyaneleyo emzimbeni okanye ukungakwazi komzimba ukusebenzisa i-insulin oyivelisa kakuhle ngenxa yeswekile eninzi egazini.
Isifo seswekile sisifo esibaluleke kakhulu. Ukungakwazi kweswekile ukungena kwiiseli kubangela ukunyuka kweswekile yegazi. Okona kubaluleke kakhulu, kunokubangela isifo sentliziyo, ukusilela kwezintso, kunye nobumfama ukuba ayiphathwanga. Uhlobo loku-1 lweswekile alunanto yakwenza nendlela yokuphila. Sisifo esibangelwa yi-immune system ihlasela izicubu zayo.Ngelixa i-Type 1 Diabetes (T1D) yayisisifo esibulalayo kumaxesha amandulo, ngenxa yeenguqu kumayeza, unyango lwexeshana lufunyenwe kunye nokuhlukaniswa kwe-insulin.
Ngaba iSifo seswekile soku-1 sinokunyangwa?
Ewe, kunokwenzeka ukunyanga isifo seswekile sohlobo loku-1. Eyokuqala ibandakanya isigulana esithatha i-insulin ngokuqhubekayo ukusuka ngaphandle. Nangona ingelonyango olupheleleyo, ilungelelanisa ixabiso lebhayoloji yesigulana. Yindlela efanele ukusetyenziswa ubomi bayo bonke. I sibini unyango lwe-stem cell. Indlela yonyango efunyenwe kunye ne uphuhliso lwamayeza anamhlanje lwenza ukuba izigulana ezinesifo seswekile zinyangwe ngokugqibeleleyo nangokusisigxina. Indlela yokuqala yonyango yindlela ebangela ukuhla kwemigangatho yokuphila kwaye ibangele ukuxhomekeka rhoqo kwiziyobisi. Ngesi sizathu, izigulana zikhetha ukufumana unyango ngokuthatha unyango lwe-stem cell.
Yintoni unyango lweStem Cell kuHlobo loku-1 lwesifo seswekile?
Unyango lweStem Cell lubandakanya ukuphuhlisa nokuphindaphinda iiseli ezithathwe kwi i-pancreatic ducts ye-diabetics kwindawo yelabhoratri kwaye ifakwe kwi-pancreas. Ngaloo ndlela, i-pancreas yesigulana iphilisa ngeeseli ezintsha kwaye yenza ukuveliswa kwe-insulin kuqheleke. Emva konyango, imfuno ye-insulin yesigulane iyancipha. Ngelo xesha, inkqubo ye-cardiovascular system, isibindi, impilo jikelele kunye nomgangatho wobomi bezigulane ziphucula.
Lusebenza njani unyango lweStem Cell kuHlobo loku-1 lweswekile?
Iiseli ze-Stem ezithathwe kwisigulane ziyaphuhliswa, zohlulwe kwaye ziphindaphindwe kwindawo yelabhoratri. Oku kuthetha ukuba zinokuguqulwa zibe ziiseli ze-beta. Iiseli zeBeta ziiseli ezinokuvelisa iswekile. Xa ezi seli zitofelwe kwi-pancreas yomntu onesifo seswekile, ukuveliswa kweglucose yesigulana kuya kuba lula.. Ngamanye amaxesha inokusetyenziswa kunyango lwezigulane ezingakwazi ukuvelisa i-insulin, kwaye ngamanye amaxesha kunyango lwezigulane ezivelisa i-insulin eyaneleyo.
Ngaba Uhlobo loku-1 lwesifo seswekile luyasebenza?
Ewe. Ngokutsho kophando, uhlobo lwe-1 yeswekile lunokunyangwa nge-stem cell transplantation. Ukusukela kumaxesha amandulo, esi sifo, esaphathwa okwethutyana nge-insulin yangaphandle, ngoku sinonyango oluqinisekileyo. Kwi-2017, izigulane ze-21 zesifo sikashukela zifakwe kwisifundo. Izigulana ezifumene i-stem cell infusion zikwazi ukuqhubeka nobomi bazo ngaphandle kwe-insulin yangaphandle iminyaka emininzi.
Iziphumo, ezipapashwe kwijenali yeFrontiers kwi-Immunology ngo-2017, zibonise ukuba uninzi lwezigulane zihlala ngaphandle kwe-insulin iminyaka emithathu enesiqingatha, kwaye isigulane esinye asizange sisebenzise i-insulin iminyaka esibhozo.
Ngawaphi amazwe endinokuthi ndilufumane unyango lweStem Cell kuHlobo loku-1 lweswekile?
Liyinyaniso elokuba oku kunokwenziwa kumazwe angaphezu kwelinye. Nangona kunjalo, uphando oluyimfuneko kufuneka lwenziwe kunyango oluyimpumelelo. Ukufumana unyango kwiilabhoratri eziyimpumelelo kunye neekliniki ezinezixhobo ezaneleyo zilingana ngokuthe ngqo nezinga lempumelelo yonyango. Ngesi sizathu, iUkraine lilizwe elikhethwa zizigulane ezininzi kunyango. Ungaqhubeka ufunda inqaku ukuze ufunde ngakumbi malunga neekliniki zaseUkraine apho ungafumana khona unyango lwe-stem cell.
I-Stem Cell Therapy For Type 1 Diabetes in Ukraine
Ungaqhagamshelana nathi ukuze ufumane okuqinisekileyo kunye nokusisigxina unyango cell stem kwiikliniki e Ukraine. Siyaqinisekisa ukuba ufumana unyango olunezinga eliphezulu lempumelelo kwiikliniki ezisemgangathweni. Ngale ndlela, uyakuphepha ukuphulukana nemali kunye nokufumana unyango olunempumelelo engaqinisekanga kwamanye amazwe. Unyango lwe-stem cell kwi-diabetes ayenziwa kwiiklinikhi ezininzi. Kukho iikliniki zabucala zoku. Ngamanye amaxesha kunzima ukufumana abona banamava kwaye baphumelele phakathi kwezi kliniki. Nangona kunjalo, unokwenza kube lula ngokuqhagamshelana nathi.
Iilebhu ezisetyenziswa kwiStem Cell Therapy eUkraine
Ukuba kukho inqaku elibaluleke kakhulu kunyango lwe-stem cell, ziilabhoratri. Ukuphuhliswa okuyimpumelelo kweeseli ezithathwe kwi-pancreatic duct, iilebhu ezinezixhobo eziphezulu kunye nezixhobo ezisemgangathweni zifunekayo. Enkosi kwezi lebhu, izinga lokuphumelela kunyango lwesigulana liphezulu. Ngenxa yesi sizathu, isigulane kufuneka sikhethe iklinikhi efanelekileyo. Ngaphandle koko, kuya kuphepheka ukufumana umphumo wonyango wexeshana.
Lithini inqanaba leMpumelelo yoNyango lweStem Cell kuHlobo loku-1 lwesifo seswekile?
Oku kuya kwahluka ngokuxhomekeke kumgangatho wekliniki apho unyangwa khona. Kwizifundo zokuqala, izinga lokuphumelela kwezigulane lalingama-40%. Isigulana sasikwazi ukuphila ngaphandle kokuthatha i-insulin yangaphandle. Noko ke, oku kwaba kokwexeshana. Isigulana, esinokuphila ngaphandle kwe-insulin i-avareji yeminyaka emi-3, emva koko kufuneka sithathe i-insulin ngaphandle kwakhona. Ezi zifundo zagqitywa ngo-2017 ngolu hlobo. Ngezifundo eziqhubekayo, abaguli ngoku banokuphila ngaphandle kwe-insulin ixesha elide kakhulu, ngamanye amaxesha ngaphandle kokufuna i-insulin ubomi babo bonke. Unokufumana amaxabiso ezigulane ezifumene unyango kwiiklinikhi zethu ngezantsi.
Lwenziwa njani unyango lweStem Cell Inyathelo ngeNyathelo?
- Okokuqala, isigulana siyalaliswa okanye sithotywe. Ngaloo ndlela, kuyathintelwa ukuba ungeva naziphi na iintlungu.
- Emva koko iqala ngokuqokelela iiseli kumjelo wepancreatic wesigulane kunye nesirinji enencam engqindilili.
- Iiseli eziqokelelweyo zithunyelwa elabhoratri.
- Amafutha okanye iiseli zegazi ezithathwe elabhoratri zohlulwe ngeeseli zesiqu. kule nto, isisombululo sixutywe kunye nesampuli ethathwe ngesirinji. Iiseli ze-stem ezihlukeneyo zithathwa kwi-tube ngoncedo lwesirinji kwaye iiseli ze-stem zihlanjululwa ngokupheleleyo usebenzisa isixhobo se-centrifuge.
- Ngaloo ndlela, i-100% yeeseli ze-stem zifunyenwe.
- I-stem cell efunyenweyo iphinda ifakwe kwi-pancreas yesigulane kwaye inkqubo igqityiwe.
Ngaba unyango lweStem Cell lunyango olubuhlungu?
Ngokuqhelekileyo, isigulane siphantsi kwe-anesthesia jikelele okanye i-sedation. Ngenxa yesi sizathu, akeva ntlungu ngexesha lotyando. Emva kotyando, akuyondlela yonyango ebuhlungu njengoko kungekho manxeba okanye izithungo ezifunekayo.
Kufuneka ndenze ntoni ukuze ndifumane unyango lweStem Cell kuHlobo loku-1 lwesifo seswekile?
Okokuqala kuya kufuneka uqhagamshelane nathi. Kuba kukho unyango olungelula. Lunyango ekungamelanga ukuba lwenziwe kwilizwe ngalinye nakuzo zonke iikliniki. Ngoko ke, kufuneka unyangwe kwiiklinikhi eziyimpumelelo. Akufunekanga ufumane unyango kwiikliniki apho ungaqinisekanga ukuba yikliniki eyimpumelelo okanye hayi. Ke ngoko, xa unxibelelana nathi, unokuzuza kuqala kwinkonzo yethu yokucebisa. Ungabuza yonke imibuzo yakho malunga nonyango lwe-stem cell. Emva koko, unokuthetha nogqirha oyingcali kwaye ufunde iimviwo eziyimfuneko kunye nohlalutyo. Ngale ndlela unokuphuhlisa isicwangciso sonyango.
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